The Journal of the American Osteopathic Association

doi: 10.7556/jaoa.2015.027

Abstract

Context: Osteopathic manipulative treatment (OMT) has been recognized as a management option for carpal tunnel syndrome (CTS), although limited research exists to substantiate its effectiveness.

Objective: To evaluate the effectiveness of OMT in the management of CTS.

Methods: This single-blinded quasi-controlled trial was conducted at an academic institution. Participants with CTS underwent weekly OMT sessions for 6 consecutive weeks. The main outcome measures were the Boston Carpal Tunnel Syndrome Questionnaire (BCTQ), a sensory symptom diagram (SSD), patient estimate of overall change, electrophysiologic testing of the median nerve (trans–carpal tunnel motor and sensory nerve conduction velocity and amplitude ratio), and carpal tunnel ultrasound imaging of the cross-sectional area of the median nerve and transverse carpal ligament length and bowing. All outcome measures were administered to participants before the first OMT session. Immediately after the first session, electrophysiologic testing of the median nerve and ultrasound imaging of the carpal tunnel were repeated. After 6 weeks of OMT, all outcome measures were readministered.

Results: Results of the BCTQ revealed statistically significant improvements in symptoms and function after 6 weeks of OMT (F=11.0; P=.004), and the improvements tended to be more pronounced on the treated side. The drop in SSD scores after 6 weeks of treatment was statistically significant (F=4.19; P=.0002). Patient estimate of overall improvement of symptoms was statistically significant for the treated side. No statistically significant changes in electrophysiologic function of the median nerve, cross-sectional area of the median nerve, or transverse carpal ligament bowing were observed. After treatment, the increase in transverse carpal ligament length was statistically significant, but no side-to-side difference was detected.

Conclusion: Osteopathic manipulative treatment resulted in patient-perceived improvement in symptoms and function associated with CTS. However, median nerve function and morphology at the carpal tunnel did not change, possibly indicating a different mechanism by which OMT acted, such as central nervous system processes.

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Chiropractic & Manual Therapies

doi: 10.1186/s12998-014-0050-7

Abstract

Practitioners in several of the health care professions use anatomical landmarks to identify spinal levels, both in order
to enhance diagnostic accuracy and to specifically target the site of intervention. Authoritative sources usually state
the upright inferior scapular angle (IAS) aligns with the spinous process (SP) of T7, but some specify the T7-8 interspace
or the T8 SP. The primary goals of this study were to systematically review the relevant literature; and conduct a
meta-analysis of the pooled data from retrieved studies to increase their statistical power. Electronic searching
retrieved primary studies relating the IAS to a spinal level, as determined by an imaging reference standard, using
combinations of these search terms: scapula, location, landmark, spinous process, thoracic vertebrae, vertebral level,
palpation, and spine. Only primary studies were included; review articles and reliability studies related to scapular
position but lacking spinal correlations were excluded. Eight-hundred and eighty (880) articles of interest were
identified, 43 abstracts were read, 22 full text articles were inspected, and 5 survived the final cut. Each article (with one
exception) was rated for quality using the QUADAS instrument. Pooling data from 5 studies resulted in normal distribution
in which the upright IAS on average aligns closely with the T8 SP, range T4-T11. Since on average the IAS most
closely identifies the T8 SP in the upright position, it is very likely that health professionals, both manual therapists
and others, who have been diagnosing and treating patients based on the IAS=T7 SP rule (the conventional
wisdom), have not been as segmentally accurate as they may have supposed. They either addressed non-intended
levels, or made numeration errors in their charting. There is evidence that using the IAS is less preferred than using the
vertebra prominens, and may be less preferred than using the iliac crest for identifying spinal levels Manual therapists,
acupuncturists, anesthesiologists, nurses, and surgeons should reconsider their procedures for identifying spinal
sites in light of this modified information. Inaccurate landmark benchmark rules will add to patient variation and
examiner errors in producing spine care targeting errors, and confound research on the importance of specificity
in treating spinal levels.


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The Journal of the American Osteopathic Association

doi: 10.7556/jaoa.2015.018

Abstract

Context: Myofascial release (MFR) is one of the most commonly used manual manipulative treatments for patients with soft tissue injury. However, a paucity of basic science evidence has been published to support any particular mechanism that may contribute to reported clinical efficacies of MFR.

Objective: To investigate the effects of duration and magnitude of MFR strain on wound healing in bioengineered tendons (BETs) in vitro.

Methods: The BETs were cultured on a deformable matrix and then wounded with a steel cutting tip. Using vacuum pressure, they were then strained with a modeled MFR paradigm. The duration of MFR dose consisted of a slow-loading strain that stretched the BETs 6% beyond their resting length, held them for 0, 1, 2, 3, 4, or 5 minutes, and then slowly released them back to baseline. To assess the effects of MFR magnitude, the BETs were stretched to 0%, 3%, 6%, 9%, or 12% beyond resting length, held for 90 seconds, and then released back to baseline. Repeated measures of BET width and the wound's area, shape, and major and minor axes were quantified using microscopy over a 48-hour period.

Results: An 11% and 12% reduction in BET width were observed in groups with a 9% (0.961 mm; P<.01) and 12% (0.952 mm; P<.05) strain, respectively. Reduction of the minor axis of the wound was unrelated to changes in BET width. In the 3% strain group, a statistically significant decrease (−40%; P<.05) in wound size was observed at 24 hours compared with 48 hours in the nonstrain, 6% strain, and 9% strain groups. Longer duration of MFR resulted in rapid decreases in wound size, which were observed as early as 3 hours after strain.

Conclusion: Wound healing is highly dependent on the duration and magnitude of MFR strain, with a lower magnitude and longer duration leading to the most improvement. The rapid change in wound area observed 3 hours after strain suggests that this phenomenon is likely a result of the modification of the existing matrix protein architecture. These data suggest that MFR's effect on the extracellular matrix can potentially promote wound healing.

Full text available here.

American Journal of Obstetrics & Gynecology

http://dx.doi.org/10.1016/j.ajog.2014.07.043

Abstract

OBJECTIVE: The purpose of this study was to evaluate the efficacy of osteopathic manipulative treatment (OMT) to reduce low back pain and improve functioning during the third trimester in pregnancy and to improve selected outcomes of labor and delivery.


STUDY DESIGN: Pregnancy research on osteopathic manipulation optimizing treatment effects was a randomized, placebo-controlled trial of 400 women in their third trimester. Women were assigned randomly to usual care only (UCO), usual care plus OMT (OMT), or usual care plus placebo ultrasound treatment (PUT). The study included 7 treatments over 9 weeks. The OMT protocol included specific techniques that were administered by board-certified OMT specialists. Outcomes were assessed with the use of self-report measures for pain and back-related functioning and medical records for delivery outcomes.


RESULTS: There were 136 women in the OMT group: 131 women in the PUT group and 133 women in the UCO group. Characteristics at baseline were similar across groups. Findings indicate significant treatment effects for pain and back-related functioning (P < .001 for both groups), with outcomes for the OMT group similar to that of the PUT group; however, both groups were significantly improved compared with the UCO group. For secondary outcome of meconium-stained amniotic fluid, there were no differences among the groups.


CONCLUSION: OMT was effective for mitigating pain and functional deterioration compared with UCO; however, OMT did not differ significantly from PUT. This may be attributed to PUT being a more active treatment than intended. There was no higher likelihood of conversion to high-risk status based on treatment group. Therefore, OMT is a safe, effective adjunctive modality to improve pain and functioning during the third trimester.


Key words: low back pain, osteopathic manipulation, pregnancy

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Manual Therapy

http://dx.doi.org/10.1016/j.math.2014.08.013

Abstract
Patellofemoral pain (PFP) is a common lower extremity condition observed in sports clinics. Recently, it
has been suggested that trunk motion could affect hip and knee biomechanics in the frontal plane. Thus,
the purpose of the study was compare trunk kinematics, strength and muscle activation between people
with PFP and healthy participants. In addition, the associations among trunk biomechanics, hip and knee
kinematics were analysed. Thirty people with PFP and thirty pain-free individuals participated. The peak
ipsilateral trunk lean, hip adduction, and knee abduction were evaluated with an electromagnetic
tracking system, and the surface electromyographic signals of the iliocostalis and external oblique muscle
were recorded during single-leg squats. Trunk extension and trunk flexion with rotation isometric
strength and side bridge tests were quantified using a handheld dynamometer. Compared with the
control group, the PFP group demonstrated increased ipsilateral trunk lean, hip adduction and knee
abduction (p = 0.02-0.04) during single-leg squat accompanied with decreased trunk isometric strength
(p = < 0.001e0.009). There was no between-group difference in trunk muscle activation. Only in the
control group, ipsilateral trunk lean was significantly correlated with hip adduction (r =0.66) and knee
abduction (r = 0.49); also, the side bridge test correlated with knee abduction (r = 0.51). Differences in
trunk, hip and knee biomechanics were found in people with PFP. No relationship among trunk, hip and
knee biomechanics was found in the PFP group, suggesting that people with PFP show different
movement patterns compared to the control group.

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